D1IP (Neuron-specific Vesicular Protein Calcyon, Caly, Drd1ip, Dopamine Receptor D1 Interacting Protein-Calcyon)

Size

£767.00

SKU:: D9000-05A
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 16aa of mouse D1IP (Accession #Q9DCA7) (KLH).
Format:: Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
Extra Details:: D1 dopamine receptor-interacting protein calcyon (D1IP) is a type II single transmembrane protein. D1IP belongs to neron-specific gene (NSG) family of proteins. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor drd1) and may interact with other dopamine receptor subtypes and/or GPCRs. Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. D1IP (rat: 226aa; human 217aa, mouse: 226aa; 24.6kD, mouse chromosome 7F4) D1IP2 is expressed in the pyramidal cells of prefrontal cortex, in hypothalamus and in caudate nucleus. Applications: Suitable for use in ELISA, Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-10ug/ml ELISA: 1:100,000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice