Demecolcine (N-Desacetyl-N-methylcolchicine)

Size

£364.00

SKU:: D2740-02
Molecular Weight:: 371.43
Purity:: ~90%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 477-30-5
Format:: Light Yellow to Very Dark Yellow Solid
Extra Details:: An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. Synonyms: (7S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-benzo[a]heptalen-9(5H)-one; Deacetylmethylcolchicine; Colchamin; NSC 3096; Omain; Omaine; Reichstein's F CAS No: 477-30-5 Molecular Formula: C₂₁H₂₅NO₅ Molecular Weight: 371.43 Melting Point: As Reported Solubility: As Reported Atmosphere: Inert gas Method for Determining Identity: Proton NMR (CDCl3) and Mass Spectrometry TLC Conditions: As Reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic. Store under inert atmosphere.