D1500-25M
DcR3, NT (TR6, Decoy Receptor 3, TNFRSF6B, TR6, M68)
Size
£639.00
- SKU:
- D1500-25M
- Purity:
- Purified by Ion Exchange chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to amino acids near the N-terminus of human DcR3 precursor. Epitope: within the first 50aa of DcR3.
- Format:
- Supplied as a liquid in PBS, 0.02% sodium azide.
- Extra Details:
- Decoy Receptor 3 is a 33kD member of the tumor necrosis factor receptor superfamily. DcR3 acts as a receptor for FasL and LIGHT, preventing them from binding to their cell death receptors and thereby inhibiting apoptosis. DcR3 is a soluble decoy receptor found in adult stomach, spinal cord, lymph node, trachea, spleen and lung. It may also be found in fetal lung, brain and liver. It is highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 0.5ug/ml Immunohistochemistry (Paraffin): 1ug/ml. Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer, pH 6.0 is recommended. Optimal dilutions to be determined by the researcher. Positive Control: Western Blot: Human heart lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice