DcR1 (TRAIL-R3, TRID, LIT, TRAIL Decoy Receptor1)

Size

£537.00

SKU:: D1499-03D
Application:: WB
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide of mouse DcTrailR1, a 179 amino acid protein. The 23 kD band may represent the “long-form” of this protein(1).
Format:: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
Extra Details:: First named mouse TNFRH1 (tumor necrosis factor receptor homologue 1), mouse DcTRAILR1 (decoy TRAIL receptor 1) this protein has been confirmed to be a receptor for TRAIL using ligand-receptor binding assays. However, overexpression was not found to cause NF-kB activation or apoptosis, as would be expected of a TRAIL receptor. These observations lead researchers to rename the protein DcTRAILR1, or decoy TRAIL receptor 1. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml observed size: 20 kD Optimal dilutions to be determined by the researcher. positive control: mouse spleen whole cell lysate Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.