D1038-08
DAND5 (DAN domain family member 5, CER2, Cerberus-like protein 2, CERL2, Cerl-2, CKTSF1B3, COCO, CRL2, Cysteine knot superfamily 1, BMP antagonist 3, DAN domain family member 5, DANTE, DTE, FLJ38607, GREM3, Gremlin-3, MGC126849, SP1) (Biotin)
Size
£960.00
- SKU:
- D1038-08
- Purity:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Arg23-Ala189 from human DAND5, expressed in E. coli. Species Sequence Homology: mouse (60%), Xenopus (24%).
- Clone:
- 9L819
- Format:
- Supplied as a lyophilized powder from PBS, 5% BSA. Labeled with Biotin. Reconstitute with 500ul sterile PBS.
- Extra Details:
- DAND5, also known as COCO, Dante, and CKTSF1B3, is a member of the DAN Domain family of BMP antagonists that includes DAN, Gremlin, PRDC, and Cerberus. DAND5 binds and inhibits Xnr1, BMP-4, Activin, and Wnt8. It is implicated in gastrulation and embryonic left-right axis formation. Human DAND5 shares 60% and 24% aa sequence identity with mouse and Xenopus DAND5, respectively. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA (Detection): 0.5-2ug/ml Optimal dilutions to be determined by the researcher. Matched Pair: Capture: D1038-08A Detection: D1038-08 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice