C8299-01A

CX3CR1 (Beta Chemokine Receptor-like 1, CCRL1, Chemokine C-X3-C Motif Receptor 1, CX3C Chemokine Receptor 1, C-X3-C CKR-1, CX3C CKR-1, CMK-BRL-1, CMKBLR1, CMKDR1, Fractalkine Receptor, GPR13, GPRV28, V28)

Size

£429.00

SKU:: C8299-01A
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: E. coli-expressed rat CX3CR1 amino terminal domain.
Format:: Supplied as a liquid, 0.05% sodium azide.
Extra Details:: Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine. Rat CX3CR1, also named RBS11, was first cloned from rat brainstem, pituitary and/or spinal cord cDNA libraries. A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor. The human equivalent receptor is known as V28, which has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators. Applications: Suitable for use in Western Blot, Flow Cytometry, Immunohistochemistry and Neutralization. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-1:2000 Flow Cytometry: 1:100-1:300 Immunohistochemistry: 1:100-1:300 Neutralization: calcium mobilization assays Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.