Crystallin AB (Alpha crystallin B chain, CryAB, Alpha (B)-crystallin, Rosenthal fiber componet, Heat-shock protein beta-5, HspB5, CryA2, AACRYA, Alpha crystallin B chain, CRYA2, Crystallin alpha polypeptide 2, CTPP 2, CTPP2, Heat shock 20kD like protein, Heat shock protein beta 5, HSPB5, Rosenthal fiber component)

Size

£594.00

SKU:: C7944-60A
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide made to an internal region of the human Crystallin AB protein (within residues 70-140).
Format:: Supplied as a liquid in Tris-Citrate/Phosphate, pH 7.0, 0.09% sodium azide.
Extra Details:: Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer. Applications: Suitable for use in Western Blot and Immunocytochemistry/Immunofluorescence. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Human and mouse skeletal muscle lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.