C7904-82

COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)

Size

£780.00

SKU:: C7904-82
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 17aa from human COX2 (KLH coupled).
Format:: Supplied as a liquid in 100mM Tris, pH 7.5, 0.2% BSA, 0.09% sodium azide.
Extra Details:: Two isoforms of Prostaglandin H synthase are well characterized, namely COX1 and COX2. Both forms of COX proteins are membrane associated heme proteins containing cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID (Non steroidal anti-inflammatory drugs) such as aspirin. COX2 is a 72kD protein having 60% homology to COX1. It is induced by cytokines and mitogens. Most likely, it plays a role in inflammatory diseases such as rheumatoid arthritis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1-10ug/ml using Chemiluminescence. ELISA: 1:10,000-100,000 Optimal dilutions to be determined by researcher. Control Peptide: C7904-81 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.