C7904-11B

Cortisol

Size

£594.00

SKU:: C7904-11B
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Cortisol 3 conjugated to BSA.
Clone:: 8.F.57B
Format:: Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
Extra Details:: Cortisol is a corticosteroid hormone produced by the adrenal cortex that is involved in the response to stress; it increases blood pressure, blood sugar levels, may cause infertility in women, and suppresses the immune system. Synthetic cortisol, also known as hydrocortisone, is used as a drug mainly to fight allergies and inflammation. Cortisol is synthesized from pregnenolone. The conversion involves hydroxylation of C-11, C-17, and C-21, the oxidation of C-3, and the isomerization of the C-5 double bond to C-4. The synthesis takes place in the zona fasciculata of the cortex of the adrenal glands. Applications: Suitable for use in ELISA and RIA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Affinity Constant: 1.7x10e9 L/mole Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.