C7903-79C
Corticotropin Releasing Hormone Receptor 1 (CRHR1, CRF1)
Size
£642.00
- SKU:
- C7903-79C
- Purity:
- Purified by affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to C-NEEKKSKVHYH of Corticotropin Releasing Hormone Receptor 1 at the internal region.
- Format:
- Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
- Extra Details:
- Corticotropin Releasing Hormone Receptor 1 (CRHR1 or CRF1) is a member of the corticotropin-releasing factor family of G-protein-coupled receptors that also includes CRF2. It is abundantly expressed in the CNS with major expression in the cortex, cerebellum, hippocampus, amygdala, olfactory bulb and pituitary. In the periphery, the receptors are expressed at low levels in the skin, ovary, testis and adrenal gland. It mediates stress and anxiety including stress related colonic motor activity. Applications: Suitable for use in Immunofluorescence, ELISA, Western Blot. Other applications not tested. Recommended Dilutions: Immunofluorescence: 2ug/ml ELISA: 1:32,000 Western Blot: 0.05-0.2ug/ml. ~60-70kD band observed in human brain (cerebellum) and human colon lysates (MW 47.7kD). Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice