C7850-95
Complement Factor P (CFP, BFD, Factor P, PFC, PFD, Properdin, Properdin P Factor Complement)
Size
£843.00
- SKU:
- C7850-95
- Purity:
- Purified by Protein A affinity chromatography
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Native purified factor P from human serum
- Clone:
- 10B2571 (10-18)
- Format:
- Supplied as a liquid in borate buffered saline, pH 8.2, 0.09% sodium azide
- Extra Details:
- Factor P is a 53kD glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections. Applications: Suitable for use in ELISA, Functional Assays, Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry; 1:1000 Immunohistochemistry (Frozen): 1:1000 Optimal dilutions to be determined by the researcher. Recommended Positive Control: Kidney from post strepoccal glomerulonephritis patients Recommended Secondary Antibodies: I1904-06C: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo I1904-06H: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice