C7510-19E
Collagen Type II
Size
£843.00
- SKU:
- C7510-19E
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Collagen type II extracted and purified from human cartilage.
- Format:
- Supplied as a liquid in PBS, 0.1% mannitol, 0.1% dextran. No preservative added.
- Extra Details:
- This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. Applications: Suitable for use in Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Immunofluorescent (Indirect) staining of cryostat sections or cultured cells: 1:10-1:20 ELISA: 1:1000 Western Blot: 1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice