C5851-80F

Clostridium botulinum Toxin A (BoNT/A, Bontoxilysin-A)

Size

£460.00

SKU:: C5851-80F
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Type A Neurotoxin and Complexing Proteins Toxoid.
Format:: Supplied as a liquid in PBS, pH 7.2, 20% glycerol. No preservative added.
Extra Details:: Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln--Arg-198 bond of SNAP-25. Applications: Suitable for use in ELISA, Dot Blot and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 1:10,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.