Clavulanic Acid, Potassium Salt (MM 14151, Potassium Clavulanate)

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£320.00

SKU:: C5836
Molecular Weight:: 237.25
Purity:: ≥96%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 61177-45-5
Format:: Brownish orange solid
Extra Details:: Clavulanic acid is a beta-lactam antibiotic produced by several species of the genus Streptomyces. The free acid degrades and is isolated and maintained as either the sodium or potassium salt. Clavulanate is a weak antibiotic but is a potent inhibitor of beta- lactamases. In combination with penicillin and cephalosporins it shows potent synergistic activity. Clavulanic acid is a suicide inhibitor, covalently binding to a serine residue in the active site of the beta-lactamase. Synonyms: Timentin; Ticarcillin; MM 14151; [2R-(2α,3Z,5α)]-3-(2-hydroxyethylidene)-7-oxo-4-oxa- 1-azabicyclo[3.2.0]heptane-2-carboxylate potassium salt CAS No: 61177-45-5 Molecular Formula: C8H8KNO5 Molecular Weight: 237.25 Appearance: Brownish orange solid Purity: ≥95% Melting Point: >170.5°C (dec) Solubility: Water (Hot, Sparingly) Atmosphere: Inert Gas Method for Determining Identity: Proton NMR (D2O) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: C18; Acetonitrile: Water= 9:5; Visualized with UV and Ninhydrin; single spot, Rf= 0.55 Potassium: ~16% by Ion chromatography Elemental Analysis: Calculated: %C: 40.50, %H: 3.40, %N: 5.90 Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic. Store under Inert atmosphere.

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