C5818

Cks2 (Cdc kinase subunit 2)

Size

£709.00

SKU:: C5818
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Synthetic peptide corresponding to the C-terminal region of human Cks2.
Clone:: 3G109
Format:: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Extra Details:: The Cks proteins are components of the cyclin-dependent kinase(CDK)/cyclin complexes that regulate mitosis. Thus, Cks proteins play important roles during the cell cycle1. Cks2 belongs to the highly conserved Suc1/Cks family of proteins that can bind to certain CDKs and are required for cell-cycle progression. Cks proteins may regulate the catalytic activity of the cdk2/cyclin A complex, as they have been shown to inhibit the activation of cdk2. The Cks2 gene has been localized to 9q22, which places it close to a putative tumor suppressor locus. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: ELISA: 0.1-1ug/ml Western Blot: 1-3ug/ml Immunoprecipitation: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: CKS2 transfected cells and HeLa cells Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.