C5818-ML490

Cks2 (Cdc kinase subunit 2) (MaxLight 490)

Size

£914.00

SKU:: C5818-ML490
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Synthetic peptide corresponding to the C-terminal region of human Cks2.
Clone:: 3G109
Format:: Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight™490.
Extra Details:: MaxLight™ 490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. The Cks proteins are components of the cyclin-dependent kinase(CDK)/cyclin complexes that regulate mitosis. Thus, Cks proteins play important roles during the cell cycle1. Cks2 belongs to the highly conserved Suc1/Cks family of proteins that can bind to certain CDKs and are required for cell-cycle progression. Cks proteins may regulate the catalytic activity of the cdk2/cyclin A complex, as they have been shown to inhibit the activation of cdk2. The Cks2 gene has been localized to 9q22, which places it close to a putative tumor suppressor locus. Applications: Suitable for use in FLISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: FLISA: 0.1-1ug/ml Western Blot: 1-3ug/ml Immunoprecipitation: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: CKS2 transfected cells and HeLa cells Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

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