C5818-FITC
Cks2 (Cdc kinase subunit 2) (FITC)
Size
£914.00
- SKU:
- C5818-FITC
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to the C-terminal region of human Cks2.
- Clone:
- 3G109
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Fluorescein isothiocyanate (FITC).
- Extra Details:
- The Cks proteins are components of the cyclin-dependent kinase(CDK)/cyclin complexes that regulate mitosis. Thus, Cks proteins play important roles during the cell cycle1. Cks2 belongs to the highly conserved Suc1/Cks family of proteins that can bind to certain CDKs and are required for cell-cycle progression. Cks proteins may regulate the catalytic activity of the cdk2/cyclin A complex, as they have been shown to inhibit the activation of cdk2. The Cks2 gene has been localized to 9q22, which places it close to a putative tumor suppressor locus. Applications: Suitable for use in FLISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: FLISA: 0.1-1ug/ml Western Blot: 1-3ug/ml Immunoprecipitation: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: CKS2 transfected cells and HeLa cells Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice