C5818-BIOTIN
Cks2 (Cdc kinase subunit 2) (Biotin)
Size
£914.00
- SKU:
- C5818-BIOTIN
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to the C-terminal region of human Cks2.
- Clone:
- 3G109
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Biotin.
- Extra Details:
- The Cks proteins are components of the cyclin-dependent kinase(CDK)/cyclin complexes that regulate mitosis. Thus, Cks proteins play important roles during the cell cycle1. Cks2 belongs to the highly conserved Suc1/Cks family of proteins that can bind to certain CDKs and are required for cell-cycle progression. Cks proteins may regulate the catalytic activity of the cdk2/cyclin A complex, as they have been shown to inhibit the activation of cdk2. The Cks2 gene has been localized to 9q22, which places it close to a putative tumor suppressor locus. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: ELISA: 0.1-1ug/ml Western Blot: 1-3ug/ml Immunoprecipitation: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: CKS2 transfected cells and HeLa cells Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice