CI-994, Free Base (4-(Acetylamino)-N-(2-aminophenyl)benzamide, Acetyldinaline, 5'-Deoxy-5-fluoro-N-((pentyloxy)carbonyl)cytidine, Goe 5549, Gö 5549, PD 123654, Tacedinaline)

Size

£212.00

SKU:: C5071-65
Molecular Weight:: 269.3
Purity:: ~99%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 112522-64-2
Format:: Supplied as a white to off-white powder.
Extra Details:: CI-994 is a histone deacetylase (HDAC) inhibitor and induces histone hyperacetylation in living cells. CI-994 inhibited HDAC-1 and HDAC-2 but not the prototypical histone acetyltransferase GCN5. Melting Point: 235-242ºC Solubility: Soluble in DMSO at 66mg/ml; very poorly soluble in ethanol and water; maximum solubility in plain water is estimated to be about 25-100uM. Buffers, serum, or other additives may increase or decrease the aqueous solubility. Elemental Anaylsis: Calculated: C=66.90% H=5.61% N=15.60% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.