Chromogranin A (CgA, CHGA, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I)

Size

£767.00

SKU:: C5069-96P
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Sheep
Immunogen:: Synthetic peptide corresponding to aa1-15, LPVNSPMNKGDTEVM of native human Chromogranin A, conjugated to KLH. Species Sequence Homology: bovine, chimpanzee, canine, equine, porcine, mouse and rat
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Chromogranin A is a secreted peptide that inhibits glucose-induced insulin release. Chromogranin A is an activator of microglia (Taupenaut et al. 1996) and is notably upregulated and prominantly expressed in the senile plaques associated with Alzheimer's disease (Yasuhara et al. 1994). Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Paraffin): 1:25-1:100. Requires protein digestion pre-treatment of paraffin sections. Pronase is recommended for this purpose Optimal dilutions to be determined by the researcher. Immunohistochemistry Positive Control: Human pancreas Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.