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C5039-01B

CHMP2A, Recombinant Human (Chromatin Modifying Protein 2A, BC2, BC-2, Charged multivesicular body protein 2a, CHMP2, CHMP2a, Chromatin-modifying protein 2a, hVps2-1, Vacuolar protein-sorting-associated protein 2-1, VPS2, Vps2-1, VPS2A)

Size

£576.00

SKU:
C5039-01B
Molecular Weight:
27.2
Purity:
~90% by SDS-PAGE Purified by immunoaffinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Format:
Supplied as liquid in 20 mM Tris-HCl buffer, pH8.0, 0.1 M NaCl 1mM DTT, and 30% glycerol
Extra Details:
CHMP2A, also known as chromatin modifying protein 2A, belongs to the SNF7 family and it is component of the ESCRT III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. Recombinant CHMP2A protein, fused to His-tag at N-terminus, , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant human CHMP2A, 1aa-222, His-tagged, expressed in E. coli Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MDLLFGRRKT PEELLRQNQR ALNRAMRELD RERQKLETQE KKIIADIKKM AKQGQMDAVR IMAKDLVRTR RYVRKFVLMR ANIQAVSLKI QTLKSNNSMA QAMKGVTKAM GTMNRQLKLP QIQKIMMEFE RQAEIMDMKE EMMNDAIDDA MGDEEDEEES DAVVSQVLDE LGLSLTDELS NLPSTGGSLS VAAGGKKAEA AASALADADA DLEERLKNLR RD Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice