Chlamydia trachomatis MOMP (Major Outer Membrane Protein)

Size

£486.00

SKU:: C4250-70D
Purity:: Purified IgG fraction to a purity of >95%.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Chlamydia trachomatis strain L2, purified Major Outer Membrane Protein (MOMP).
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. No stabilizing proteins have been added.
Extra Details:: Chlamydia is caused by the bacterium Chlamydia trachomatis. The intracytoplasmic inclusions caused by the bacterium are draped around the infected cell’s nucleus. Chlamydia has a genome size of approximately 500-1000 kilobases and contains both RNA and DNA. The organism is also extremely temperature sensitive and must be refrigerated at 4°C as soon as a sample is obtained. Colonization of Chlamydia begins with attachment to sialic acid receptors on the eye, throat or genitalia. It persists at body sites that are inaccessible to phagocytes, T-cells and B-cells. It also exists as 15 different serotypes. These serotypes cause four major diseases in humans: endemic trachoma (caused by serotypes A and C), sexually transmitted disease and inclusion conjunctivitis (caused by serotypes D and K), and lymphogranuloma venereum (caused by serotypes L1, L2, and L3). Studies reveal that Chlamydia, because of its cell wall, is able to inhibit phagolysosome fusion in phagocytes. Applications: Suitable for use in ELISA and Immunofluorescence. It is also suitable for Conjugation purposes. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Titer: >1:1000 by indirect Immunofluorescence vs. all serovars (A-K, L1-L3) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice