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C2777-95

Ceramide

Size

£927.00

SKU:
C2777-95
Purity:
Purified by gel filtration on sephacryl S-300 from ascites.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Ceramide (sphingosine-[trans-D-erythro-2-amino-4-octadecene-1,3-diol]), conjugated to BSA.
Clone:
6D311 (MID 15B4)
Format:
Supplied as a liquid in PBS, pH 7.2, 0.1% BSA, 0.09% sodium azide.
Extra Details:
Ceramides are a family of lipid molecules. A ceramide is composed of sphingosine and a fatty acid. Ceramides are found in high concentrations within the cell membrane of cells. They are one of the component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer. For years, it was assumed that ceramides and other sphingolipids found in the bilayer cell membrane were purely structural elements. This is now known to be not completely true. Ceramide can actually act as a signaling molecule. The most well-known functions of ceramides as cellular signals include regulating the differentiation, proliferation, programmed cell death (PCD), and apoptosis (Type I PCD) of cells. Applications: Suitable for use in ELISA, Flow Cytometry, Immunocytochemistry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: 1:10 Flow Cytometry: 20ul/test Immunohistochemistry (Paraffin): 1:10 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice