C2589-94

CEBP gamma, DNA Binding Domain, Recombinant, Human, aa39-147, His-Tag (CCAAT Enhancer Binding Protein, gamma)

Size

£819.00

SKU:: C2589-94
Molecular Weight:: 16.5
Purity:: Purified by conventional chromatography techniques (≥ 95% by SDS PAGE).
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 0.1M sodium chloride, 5mM beta-Mercaptoethanol.
Extra Details:: CCAAT/enhancer binding protein (C/EBP) gamma is a family of transcription factors all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP alpha, beta, gamma, delta, that form homodimers and/or form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein; a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBP gamma may cooperate with Fos to bind PRE-enhancer elements. The DNA binding domain of CEBP gamma (amino acid residues, 39-147) was produced in E .coli and purified by using conventional chromatography techniques. Molecular Weight: 16.5kD (146 amino acids) Sequence: MRGSHHHHHH/ GMASMTGGQQ/ MGRDLYDDDD/ KDRWGSMPGG/ GGKAVAPSKQ/ SKKSSPMDRN/ SDEYRQRRER/ NNMAVKKSRL/ KSKQKAQDTL/ QRVNQLKEEN/ ERLEAKIKLL/ TKELSVLKDL/ FLEHAHNLAD/ NVQSISTENT/ TADGDN Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice