C2581-01D-PE
CDR2 (Cerebellar Degeneration-related Protein 2, Paraneoplastic Cerebellar Degeneration-associated Antigen, Major Yo Paraneoplastic Antigen, PCD17) (PE)
Size
£914.00
- SKU:
- C2581-01D-PE
- Purity:
- Purified.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- CDR2 (NP_001793, 296-405aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
- Clone:
- 4F5
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
- Extra Details:
- CDR2 (Cerebellar degeneration related protein 2) is an onconeuronal antigen; i.e. an antigen that is expressed by systemic tumors and elicits an immune response that may develop into an autoimmune neuronal degeneration. Paraneoplastic cerebellar degeneration (PCD) is a disorder in which breast or ovarian tumors express CDR2, which normally is expressed in cerebellar Purkinje neurons. Patients with PCD carry a characteristic antibody called anti-Yo. Anti-Yo sera reacts with at least 2 antigens, a major species CDR2, and a minor species CDR1. Applications: Suitable for use in FLISA, Immunofluorescence, and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice