C2562-83
CDC42 Binding Protein Kinase alpha (CDC42-binding Protein Kinase alpha, DMPK-like alpha, CDC42BPA, FLJ23347, KIAA0451, Myotonic Dystrophy Kinase-related CDC42-binding Kinase alpha, Myotonic Dystrophy Protein Kinase-like alpha, Serine/threonine-protein Kinase MRCK alpha, MRCK alpha) (Azide Free)
Size
£685.00
- SKU:
- C2562-83
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to a portion of amino acids within aa551-650 of human CDC42BPA.
- Clone:
- 10B2176
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
- Extra Details:
- The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 ELISA: 1ug/ml-3ng/ml Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice