C2562-83-ML550
CDC42 Binding Protein Kinase alpha (CDC42-binding Protein Kinase alpha, DMPK-like alpha, CDC42BPA, FLJ23347, KIAA0451, Myotonic Dystrophy Kinase-related CDC42-binding Kinase alpha, Myotonic Dystrophy Protein Kinase-like alpha, Serine/threonine-protein Kinase MRCK alpha, MRCK alpha) (Azide Free) (MaxLight 550)
Size
£914.00
- SKU:
- C2562-83-ML550
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to a portion of amino acids within aa551-650 of human CDC42BPA.
- Clone:
- 10B2176
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
- Extra Details:
- MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 FLISA: 1ug/ml-3ng/ml Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice