C2549-22Q
CD274 (B7-h1 Protein, B7-H1, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1) (APC)
Size
£837.00
- SKU:
- C2549-22Q
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Phe19-Thr239 from human B7-H1, NSO-derived.
- Clone:
- 12K56
- Format:
- Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
- Extra Details:
- B7-H1, also known as PD-L1 and CD274, is a 50kD type I transmembrane protein belonging to the B7 family. B7-H1 contains one Ig-like C2-type domain and one Ig-like V-type domain. It is constitutively expressed in several tissues and is up-regulated on various tumors and activated dendritic cells, macrophages, and B cells. B7-H1 interacts with PD-1 on T cells to limit T cell activation and regulate immune tolerance. Within the extracellular region, mouse and human B7-H1 share 73% aa sequence identity. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Excitation: 620-650nm Emission: 660-670nm Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice