C2548-97A
CD221 (Insulin-like growth factor I Receptor, IGF-I Receptor)
Size
£691.00
- SKU:
- C2548-97A
- Purity:
- Purified by Protein G affinity chromatography from tissue culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Purified human placental IGF-I receptor.
- Clone:
- 6A396 (1H7)
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
- Extra Details:
- Human CD221 is a 155kD receptor tyrosine kinase, also known as Insulin-like growth factor I receptor (IGF-I Receptor). CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signalling proteins. Applications: Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Flow Cytometry: 1:10. Use 10ul to label 10e6 cells in 100ul. Immunohistochemistry (Paraffin): 1:10-1:40. Protein digestion is required Optimal dilutions to be determined by the researcher. Immunohistochemistry Positive Control: Pancreas, placenta Recommended Negative Control: I1904-78R: IgG1 Murine Negative Control Hybridoma: BALB/c mice were fused with cells of the SP2/0 myeloma cell line Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice