C2548-96Y1
CD206 (MR, Mannose Receptor C Type I)
Size
£863.00
- SKU:
- C2548-96Y1
- Purity:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Recombinant protein corresponding to Leu19-Lys1383 (Thr399Ala & Leu407Phe) of human Macrophage Mannose Receptor, expressed in NS0 cells.
- Clone:
- 7H24
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Extra Details:
- MMR, also known as CD206 and MRC1 (mannose receptor C, type 1), is a scavenger receptor that is expressed on tissue macrophages, myeloid dendritic cells, and liver and lymphatic endothelial cells. MMR contains eight carbohydrate recognition domains (CRD) which enable the internalization of a wide variety of soluble and pathogen-associated glycans. Once internalized, ligands are released following acidification of phagosomes or endosomes, and the receptor is recycled to the cell surface. Applications: Suitable for use in Immunocytochemistry and Direct ELISA. Other applications not tested. Recommended Dilutions: Immunocytochemistry: 8-25ug/ml using immersion fixed human peripheral blood mononuclear cells. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice