C2548-90C
CD163 (Hemoglobin/Haptoglobin Complex Receptor, M130 antigen, Ber-Mac3, Ki-M8, SM4) (Biotin)
Size
£1,055.00
- SKU:
- C2548-90C
- Purity:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Gly41-Ser1045 from human CD163 expressed in NS0 cells. Species Sequence Homology: mouse; 74%, rat; 75%, bovine; 84%, equine; 86%, porcine; 86%, and canine; 87%.
- Clone:
- 9i228
- Format:
- Supplied as a lyophilized powder from PBS, BSA. Reconstitute with 500ul sterile PBS. Labeled with Biotin.
- Extra Details:
- CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA (detection): 0.5-2ug/ml Optimal dilutions to be determined by the researcher. Recommended Pair: Detection: C2548-90C Capture: C2548-89G2 Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice