C2548-87B-ML650
CD158b (p58.2) (MaxLight 650)
Size
£1,081.00
- SKU:
- C2548-87B-ML650
- Purity:
- Purified
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- NK cell clone E57
- Clone:
- 3H1906 (GL183)
- Format:
- Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.
- Extra Details:
- MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Killer cell immunoglobulin-like receptor 2DL3 is also known as CD158b, KIR-023GB, MHC class I NK cell receptor, p58 natural killer cell receptor or Natural killer-associated transcript 2. CD158b is a 341aa, ~58 kD single pass type-1 transmembrane glycoprotein containing two Ig-like C2-type domains that is expressed by a subset of NK cells. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. C2548-87B can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3. Applications: Suitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul labels 10e6 cells in 100ul. Optimal working dilutions to be determined by researcher. Hybridoma: P3UI myeloma cells with spleen cells from Balb/c mice. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice