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C2548-87B-HRP

CD158b (p58.2) (HRP)

Size

£1,081.00

SKU:
C2548-87B-HRP
Application:
IP
Purity:
Purified
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
NK cell clone E57
Clone:
3H1906 (GL183)
Format:
Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Extra Details:
Killer cell immunoglobulin-like receptor 2DL3 is also known as CD158b, KIR-023GB, MHC class I NK cell receptor, p58 natural killer cell receptor or Natural killer-associated transcript 2. CD158b is a 341aa, ~58 kD single pass type-1 transmembrane glycoprotein containing two Ig-like C2-type domains that is expressed by a subset of NK cells. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. C2548-87B can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3. Applications: Suitable for use in Immunoprecipitation. Other applications not tested. Recommended Dilutions: Optimal working dilutions to be determined by researcher. Hybridoma: P3UI myeloma cells with spleen cells from Balb/c mice. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Shipping Conditions:
Blue Ice