C2548-83N3

CD152 (CTLA4, Cytolytic T-lymphocyte-associated Antigen 4) (PE)

Size

£422.00

SKU:: C2548-83N3
Purity:: Purified
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Hamster
Immunogen:: Extracellular portion of murine CTLA-4 fused to a murine IgG2a
Clone:: 1B8
Format:: Supplied as a liquid in PBS, 0.09% sodium azide and a stabilizing agent. Labeled with R-Phycoerythrin (PE).
Extra Details:: The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors.1-4 However CD152 is thought to be a negative regulator of T cell activation1-3 and may play a role in apoptotic control of T cells. CD152 exists as a 69kD homodimer1, and is relatively conserved among humans, mice and chickens.2 Applications: Suitable for use in FLISA and Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.