C2548-80A2-BIOTIN
CD147 (CD147 Antigen, 5A11 Antigen, 5F7, Basigin, BSG, Blood Brain Barrier HT7 Antigen, Collagenase Stimulatory Factor, Emmprin, Extracellular Matrix Metalloproteinase Inducer, Leukocyte Activation Antigen M6, M6, M6 Antigen, Neurothelin, OK, OK Blood Group Antigen, Tumor Cell-derived Collagenase Stimulatory Factor, TCSF) (Azide Free) (Biotin)
Size
£893.00
- SKU:
- C2548-80A2-BIOTIN
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimer).
- Clone:
- 10B766 (MEM-M6/6)
- Format:
- Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
- Extra Details:
- CD147, otherwise known as neurothelin, is a type I transmembrane glycoprotein and member of the immunoglobulin gene superfamily, broadly expressed on peripheral blood cells, endothelial cells, and increased on T cells following activation. CD147 is also strongly expressed on small lung cancer cells and hepatocellular carcinoma. Biological properties of CD147 include the regulation of T cells, integrin functions and cell adhesion, the stimulation of metalloproteinase (MMP) production by fibroblasts, the promotion of astrocyte outgrowths, and roles in tumor progression, neuronal system function and reproduction. Applications: Suitable for use in Flow Cytometry, Functional Assays and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: detects a band of ~45-60kD in 293 human fibroblast cell lysates under non-reducing conditions. Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice