C2548-76
CD141 (Thrombomodulin, THBD, Fetomodulin, THRM)
Size
£863.00
- SKU:
- C2548-76
- Purity:
- Purity: Purified by Protein G affinity chromatography from hybridoma culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Ala19-Ser515 from human CD141 expressed in NSO cells.
- Clone:
- 9H93
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Extra Details:
- Thrombomodulin (THBD) is an endothelial-specific type I membrane receptor that inhibits coagulation and fibrinolysis. It functions primarily as a cell surface receptor and an essential cofactor for active thrombin, resulting in the activation of protein C, which in turn degrades clotting factors Va and VIIIa. Mutations in this gene can cause inherited thrombophilia. The aa sequence of human THBD is 99% and 76% identical to that of chimpanzee and mouse. Applications: Suitable for use in Flow Cytometry, ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 0.25ug labels 10e6 cells using THP-1 human acute monocytic leukemia cell line Immunohistochemistry: 8-25ug/ml using immersion fixed paraffin-embedded sections of human kidney ELISA (Capture): 2-8ug/ml Optimal dilutions to be determined by the researcher. Matched Pairs: Capture: C2548-76 Detection: T5048-10B Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice