CD115, CT (CD115 Antigen, c-fms, CFMS, Colony Stimulating Factor 1 Receptor, Colony Stimulating Factor I Receptor, CSF 1 R, CSF-1-R, CSF1R, CSFR, FIM2, FMS Proto-oncogene, Macrophage Colony Stimulating Factor 1 Receptor, MCSF Receptor, Proto-oncogene c-Fms)

Size

£696.00

SKU:: C2447-51Y
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide selected from the C-terminal region of human CSF1R (KLH).
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. This protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.