C2446-50C
CD105 (Endoglin, gp160, TGF beta1,3 Receptor)
Size
£453.00
- SKU:
- C2446-50C
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Inflamed mouse skin.
- Clone:
- 5K262 (MJ7/18)
- Format:
- Supplied as a liquid in 100mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
- Extra Details:
- CD105 (Endoglin, gp160, TGF beta1,3 Receptor) is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells. Both mouse and human CD105 exhibit > 70% sequence homology in their cytoplasmic domains with type III transforming growth factor beta (TGFb) receptor. CD105 has been shown to be one of several receptors for the various isoforms of TGFb, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response. Applications: Suitable for use in Identification and enumeration of CD105 + cells by Flow Cytometry, Immunohistochemistry, Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: ≤1ug/10e6 cells Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice