CD104 (Integrin beta4) (Not for Export EU)

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£806.00

SKU:: C2446-01C
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide from the COOH terminal, cytoplasmic domain of the human b4 integrin subunit. The sequence used is NH2- (K)GTLSTHMDQQFFQT-amide. The lysine (K) is not in the b4 sequence and was added to conjugate the peptide to the protein carrier.
Format:: Supplied as a liquid in 0.05% sodium azide.
Extra Details:: Human beta4 integrin is also known as CD104. It is a 205kD glycoprotein. It associates with the alpha6 integrin to form the alpha6/beta4 complex. CD104 is expressed on epithelial cells, Schwann cells and various tumor cell lines. Applications: Suitable for use in Immunohistochemistry and Immunopreciptiation. Other applications have not been tested. Recommended Dilutions: Immunoprecipitation: Labeled cell extract 5ul of serum is sufficient to precipitate a6b4 from 1-2x10e6 cells. In some cases immunoprecipitation from 35S methionine labeled cells originates two bands of 95 and 55kD of unknown origin in addition to the 200kD and 140kD bands corresponding to b4 and a6. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.