C2443-86H1-ML550
CD98 (4F2 Cell Surface Antigen Heavy Chain, 4F2 Heavy Chain Antigen, 4F2hc, 4T2HC, Antigen Defined by Monoclonal Antibody 4F2 Heavy Chain, CD98 Heavy Chain, CD98HC, Lymphocyte Activation Antigen 4F2 Large Subunit, MDU1, Monoclonal 44D7, NACAE, Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport) Member 2, SLC3A2) (MaxLight 550)
Size
£793.00
- SKU:
- C2443-86H1-ML550
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Thymic epithelial cells from mouse.
- Clone:
- H202-529.4.1.4
- Format:
- Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
- Extra Details:
- MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. CD98 constitutes the heavy chain of the complex and is required for the surface expression and basolateral localization of the amino acid transporter complex in polarized epithelial cells. The CD98 heavy chain also interacts with beta 1 integrins and regulates their activation through the cytoplasmic domains and transmembrane regions. Studies suggest that overexpression of CD98 may contribute to cell growth and survival by regulating integrin signalling, and therefore may play an important role in tumorigenesis. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1:20-1:200; 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Recommended Negative Control: I1904-76H: IgG1 Negative Control Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice