C2441-90H
CD91 (LRP, alpha2MR, Low Density Lipoprotein Receptor-related Protein) (PE)
Size
£767.00
- SKU:
- C2441-90H
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatographyfrom tissue culture supernatant .
- Storage Conditions:
- 4°C Do not freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Purified alpha2 macroglobulin receptor.
- Clone:
- 3H1766 (A2M ralpha-2)
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4, 5% sucrose, 1% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE). Reconstitute with 1ml sterile ddH2O.
- Extra Details:
- CD91 is also known as alpha 2-Macroglobulin receptor (A2MR), low density lipoprotein receptor-related protein (LRP) or apoliprotein E receptor (APOER). CD91 is a multifunctional cell plasma membrane receptor involved in the process of endocytosis of various ligands that are important in protease and cytokine activity regulation, and lipoprotein metabolism. CD91 expression in breast cancer cell lines T47D2 and BT-201 can be affected by both cell culture density alone and by estrogen. Heat shock proteins appear to be an integral part of the viral life cycle. The heat shock proteins interact with antigenpresenting cells (APC) through CD91 in maturation, activation and representation of foreign peptides with MHC class I molecules on their surface. Expression of CD91 was found increased in individuals, who were infected with HIV-1 for more than 10 years with no evidence of progressive disease. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recomended Dilutions: Flow Cytometry: Neat; Use 10ul to label 10e6 cells in 100ul. Optimal dilution determined by the researcher. Hybridoma: NS1 myeloma cells with spleen cells from Balb/c mice. Recommended Negative Control: I1904-79D: IgG1 Murine Negative Control (PE) Storage and Stability: Lyophilized powder may be stored at 4°C. Stable for 12 months after receipt. Reconstitute with sterile ddH2O. Aliquot and store at 4°C. DO NOT FREEZE! For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
- Shipping Conditions:
- Blue Ice