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C2441-62AX-HRP

CD90 (Thy-1 Membrane Glycoprotein, Thy-1 Antigen, Thy1, Thy-1, T25) (Azide Free) (HRP)

Size

£767.00

SKU:
C2441-62AX-HRP
Application:
ICC
Purity:
Purified
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rat
Immunogen:
Mouse T cell hybridoma C6/G8
Clone:
G7
Format:
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Extra Details:
CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain.1-4 It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains.1,2 This antibody stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex.1,5-7 The antibody has also been reported to promote apoptosis of thymocytes and CTL clones,4,7 and to mediate adhesion of thymocytes to thymic stroma.8 Applications: Suitable for use in Immunocytochemistry, In vitro T cell activation and as Induction of apoptosis. Other applications not tested. Recommended Dilution: Immunocytochemistry: Acetone-fixed, frozen sections. Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Shipping Conditions:
Blue Ice