C2431-14A1

CD79a (CD 79a, CD79A Antigen Immunoglobulin Associated alpha, CD79a Molecule Immunoglobulin Associated alpha, B Lymphocyte Specific MB1 Protein, B cell Antigen Receptor Complex Associated Protein alpha Chain, IGA, Ig alpha, Immunoglobulin Associated Alpha, Ly54, MB 1, MB 1 Membrane Glycoprotein, MB1, MB1 Membrane Glycoprotein, Membrane Bound Immunoglobulin Associated Protein, Surface IgM Associated Protein)

Size

£537.00

SKU:: C2431-14A1
Purity:: Purified by Protein A affinity chromatography from tissue culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Synthetic peptide corresponding to aa202-216 of human CD79a.
Clone:: HM57
Format:: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Extra Details:: CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ul Immunohistochemistry (Paraffin): 1:100-1:500 Requires HIER using sodium citrate buffer pH6.0 prior to staining. Membrane permeabilization is required. Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from BALB/c mice. Positive control: Human tonsil Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice