C2418-03D
CD63 (CD63 Antigen, Granulophysin, Lysosome-associated Membrane Glycoprotein 3, LAMP-3, ME491, Melanoma 1 Antigen, MLA1, Melanoma-associated Antigen ME491, Ocular Melanoma-associated Antigen, OMA81H, Tetraspanin-30, TSPAN30, Tspan-30) (FITC)
Size
£608.00
- SKU:
- C2418-03D
- Application:
- Flow Cytometry
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- HPB-ALL T cell line
- Clone:
- MEM-259
- Format:
- Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide. Labeled with fluorescein isothiocyanate (FITC).
- Extra Details:
- The CD63 antigen (Melanoma 1 antigen) is a glycoprotein of 40-60kD that belongs to the tetraspans family (TM4SF). CD63 is intracellular lysosomal/endosomal/granule protein that is translocated to cell surface upon activation of platelets, endothelial cells, and granulocytes (activation marker). CD63 is also expressed on monocytes/macrophages and endothelium. Its cellular function has not been exactly elucidated. CD63 is thought to be associated with the early stages of melanoma tumor progression (in regulation of motility and adhesion of melanoma cells). Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 20ul labels human blood cells in 100ul whole blood Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice