C2414-93S
CD62L (L-selectin, CD62 Antigen-like Family Member L, Leukocyte Adhesion Molecule 1, LAM-1, Leukocyte Surface Antigen Leu-8, Leukocyte-endothelial Cell Adhesion Molecule 1, LECAM1, Lymph Node Homing Receptor, TQ1, gp90-MEL, SELL, LNHR, LYAM1)
Size
£326.00
- SKU:
- C2414-93S
- Purity:
- Purified by affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Phorbol myristic acid activated human peripheral blood leukocytes.
- Clone:
- DREG-56
- Format:
- Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
- Extra Details:
- CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis x (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells. Applications: Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: ≤0.5ug per 10e6 cells in 100ul or 100ul whole blood. Immunohistochemistry: Reported to stain acetone-fixed frozen tissue sections. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice