C2414-17

CD61 (ITGB3, Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa)

Size

£850.00

SKU:: C2414-17
Purity:: Purified by Protein A affinity chromatography from ascites.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Normal blood mononuclear cells activated by mixed lymphocyte reaction and cultured for 10 days in medium containing IL-2.
Clone:: 2Q800 (25E11)
Format:: Supplied as a liquid in PBS, pH 7.6, 0.09% sodium azide. See C2414-16 for azide free version.
Extra Details:: CD61 (GPIIIa) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronection, von Willebrand factor and vitronectrin. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation, Immunocytochemistry and Inhibition. Other applications not tested. Recommended Dilutions: Immunocytochemistry: Acetone fixation Immunoprecipitation: Immunoprecipites a complex of the CD41 and CD61, 105kD reduced and 90kD unreduced Inhibits platelet aggregation: 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.