C2412-06T
CD58 (CD58 Antigen, Ag3, Lymphocyte Function Associated Antigen Type 3, LFA3, LFA-3)
Size
£416.00
- SKU:
- C2412-06T
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- NALM-6 human pre-B cell line
- Clone:
- 10B1840 (MEM-63)
- Format:
- Supplied as a liquid in PBS, pH 8.8, 15mM sodium azide
- Extra Details:
- CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1-4ug/ml; Cold-induced transient opalescent turbidity may appear during the storage at 2 -8°C. Bring the antibody to room temperature until the turbidity disappears, and mix well before the use. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice