C2404-47F

CD49d (a4 integrin, VLA-4 alpha chain, Integrin a4, ITGA4) (Azide Free)

Size

£448.00

SKU:: C2404-47F
Purity:: Purified by affinity chromatography. Endotoxin: ≤0.01EU/ug
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: AKR/Cum mouse spontaneous T lymphoma line TK1
Clone:: R1-2
Format:: Supplied as a liquid in PBS, pH 7.2. No preservatives added.
Extra Details:: CD49d is a 150kD glycoprotein, also known as α4 integrin or VLA-4 α chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two β chains, β1 (CD29) or β7, to form the VLA-4 (integrin α4β1) or LPAM-1 (integrin α4β7) complexes. CD49d plays a critical role in adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation, and Functional Assay (Inhibition of Binding). Other applications not tested. Recommended Dilution: Flow Cytometry: 1ug labels 10e6 cells in 100ul. Immunohistochemistry: frozen Optimal dilution to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.