C2404-46D

CD49d (Integrin alpha4, VLA4, LHR, Lymphocyte Homing Receptor) (PE)

Size

£704.00

SKU:: C2404-46D
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Human peripheral myeloma cells
Clone:: 7H169 (Bu49)
Format:: Supplied as a liquid in PBS, pH 7.2, 0.2% BSA, 0.05% sodium azide, 15% glycerol. Labeled with R-Phycoerythrin (PE).
Extra Details:: Human CD49d molecules are integrin a4 chains that are expressed as heterodimers with CD29 (b1 integrin) or (b7 integrin) and function as adhesion receptors. CD49d/CD29 is mainly expressed on thymocytes and B cells with increased expression on activated T cells. The ligands for CD49d/CD29 include VCAM-1 and fibronectin. Functional Application: Antibody blocks VLA-4 binding to VCAM-1. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only pror to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.