C2400-76
CD45RO (Thymocytes (Activated/Memory T Cells))
Size
£607.00
- SKU:
- C2400-76
- Purity:
- Supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Isolated from IL-2 dependent T cell line.
- Clone:
- UCHL1
- Format:
- Supplied as a liquid, 0.09% sodium azide.
- Extra Details:
- The CD45RO antigen is present on most thymocytes, about 40% of resting peripheral blood T-lymphocytes and the majority of T-cells in skin reactive infiltrates and T-cell malignancies. CD45RO is also found on a subset of B-cells and some B-cell lymphomas. NK cells do not express the CD45RO antigen. It is also present on monocytes, macrophages and granulocytes. Low MW (Mr 180kD) isoform of the leukocyte common antigen (LCA) is a part of a family of protein tyrosine phosphatases. When activated with phytohemagglutinin (PHA), naive T-cells lose the CD45RA antigen and begin to express the CD45RO antigen. CD45RO may be a marker for memory T-cells. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Frozen): 1:5-1:10 Immunohistochemistry (Paraffin): 1:5-1:10. Microwave treatment recommended Optimal dilutions to be determined by the researcher. Positive Control: Tonsil, thymus. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice